|
Symbol Name ID |
Atg7
autophagy related 7 MGI:1921494 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Dysphagia |
Posterior atrophy of corpus callosum |
Cerebral atrophy |
Cerebellar hypoplasia |
Ataxia |
Choreoathetosis |
Tremor |
Absent speech |
Delayed speech and language development |
Dysarthria |
Schizophrenia |
Autistic behavior |
Bruxism |
Self-mutilation |
Dyskinesia |
Dystonia |
Encephalopathy |
Delayed ability to walk |
Seizure |
| Disease(s) Associated with ATG7 | |||||||||||||||||||
| autosomal recessive spinocerebellar ataxia 31 |
| Mouse Phenotypes | nervous system phenotype |
increased neuron apoptosis |
abnormal brain morphology |
abnormal substantia nigra pars compacta morphology |
absent hippocampus pyramidal cells |
absent cerebral cortex pyramidal cells |
Purkinje cell degeneration |
astrocytosis |
gliosis |
abnormal neuron morphology |
abnormal motor neuron morphology |
abnormal dendritic spine morphology |
abnormal sensory neuron morphology |
neuron degeneration |
neurodegeneration |
axon degeneration |
abnormal nervous system physiology |
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| Availability | Mouse Genotype | |||||||||||||||||
| Atg7tm1Tchi/Atg7tm1Tchi Tg(Nes-cre)1Wme/0 (conditional) |
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| Atg7tm1Tchi/Atg7tm1Tchi Aviltm2(cre)Fawa/Avil+ (conditional) |
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| Atg7tm1Tchi/Atg7tm1Tchi Tg(SLC18A3-cre)KMisa/0 (conditional) |
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| Atg7tm1Tchi/Atg7tm1Tchi En1tm2(cre)Wrst/En1+ (conditional) |
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| Atg7tm1Tchi/Atg7tm1Tchi Slc6a3tm1(cre)Xz/Slc6a3+ (conditional) |
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| Atg7tm1Tchi/Atg7tm1Tchi Tg(Camk2a-cre)T29-1Stl/0 (conditional) |
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| Atg7tm1Tchi/Atg7tm1Tchi Tg(Nes-cre)1Kln/0 (conditional) |
* | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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